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Publications – Doering Lab
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Publications

Andrew L. Chang, Yiming Kang, and Tamara L. Doering. Cdk8 and Ssn801 regulate oxidative stress resistance and virulence in Cryptococcus neoformans. mBio 10:e02818-18, 2019. doi: 10.1128/mBio.02818-18 . PMID: 30755515 PMCID: PMC6372802

Felipe H. Santiago-Tirado, Robyn S. Klein, and Tamara L. Doering. An in vitro brain endothelial model for studies of cryptococcal transmigration into the central nervous system. Current Protocols, doi: 10.1002/cpmc.78. PMID: 30776307 PMCID: PMC6586498

Andrew L. Chang, Camaron R. Hole, and Tamara L. Doering. An automated assay to measure phagocytosis of Cryptococcus neoformans. Current Protocols, doi: 10.1002/cpmc.79. PMID: 30802005 PMCID: PMC6586510

Lucy X. Li, Camaron Hole, Matthew Williams, Javier Rangel-Moreno, Shabaana Khader, and Tamara L. Doering. Cryptococcus neoformans evades pulmonary immumity by modulating xylose transport. Infection and Immunity; doi: https://doi.org/10.1101/741017. In press.

Blake Billmyre, Shelly A. Clancey, Lucy X. Li, Tamara L. Doering, and Joseph Heitman. 5-fluorocytosine resistance is associated with hypermutation and alterations in capsule biosynthesis in Cryptococcus. Nat Commun. 11(1):127; doi: 10.1038/s41467-019-13890-z. PMID: 31913284 PMCID: PMC6949227

Felipe H. Santiago-Tirado, Michael D. Onken, John A. Cooper, Robyn S. Klein, and Tamara L. Doering. Trojan horse transit contributes to blood-brain barrier crossing of a eukaryotic pathogen. mBio, 8. doi: 10.1128/mBio.02183-16, 2017. PMID: 28143979 PMCID: PMC5285505. Media attention (click here)

Deepa L. Srikanta, Camaron Hole, Matthew Williams, Shabaana Khader, and Tamara L. Doering. RNAi interference screening reveals host CaMK4 as a regulator of cryptococcal uptake and pathogenesis. Infection and Immunity, doi: 10.1128/IAI.00195-17, 2017. PMID: 28970273 PMCID: PMC5695120.

Rajendra  Upadhya, Woei C. Lam, Brian Maybruck, Maureen J. Donlin, Andrew L. Chang, Sarah Kayode, Kate L. Ormerod, James A. Fraser, Tamara L. Doering, and Jennifer K. Lodge. A fluorogenic C. neoformans reporter strain with a robust expression of m-cherry expressed from a safe haven site in the genome. Fungal Genetics and Biology, 108, 13-25; doi: 10.1016/j.fgb.2017.08.008, 2017. PMID: 28870457 PMCID: PMC5681388.

Lucy X. Li, Angel Ashikov, Hong Liu, Cara L. Griffith, Hans Bakker, and Tamara L. Doering. Cryptococcus neoformans UGT1 encodes a UDP-Galactose/UDP-GalNAc transporter. Glycobiology, 27, 87-98; doi: 10.1093/glycob/cww078, 2017. PMID: 27496760 PMCID: PMC5193108.

REVIEW ARTICLE:Felipe Santiago-Tirado and Tamara L. Doering. False friends: Phagocytes as Trojan horses in brain infections. PLOS Pathogens, doi: 10.1371/journal.ppat.1006680, 2017. PMID: 29240825 PMCID: PMC5730104.

Lucy X. Li, Carsten Rautengarten, Joshua L. Heazlewood, and Tamara L. Doering. Xylose donor transport is critical for fungal virulence. PLoS Pathogens, 14, doi: 10.1371/journal.ppat.1006765, 2018. PMID: 29346417 PMCID: PMC5773217.

Andrew L. Chang and Tamara L. Doering. Maintenance of mitochondrial morphology in Cryptococcus neoformans is critical to stress resistance and virulence. mBio 10:e01375-18; doi: 10.1128/mBio.01375-18, 2018. PMID: 30401774 PMCID:PMC6222134.

Lucy X. Li, Carsten Rautengarten, Joshua L. Heazlewood, and Tamara L. Doering. UDP-glucuronic acid transport is required for virulence of Cryptococcus neoformans. mBio, 30, doi: 10.1128/mBio.02319-17, 2018. PMID: 29382737 PMCID: PMC5790919.

Ryan Friedman, Stacey R. Gish, Holly Brown, Lindsey Brier, Nicole Howard, Tamara L. Doering, and Michael R. Brent. Unintended side effects of transformation are very rare in Cryptococcus neoformans. G3: Genes, Genomes, Genetics, 8, 377-383; doi: 10.1534/g3.117.300357, 2018. PMID: 29305388 PMCID: PMC5844303.

REVIEW ARTICLE: Daniel P. Agustinho, Liza C. Miller, Lucy X. Li, and Tamara L. Doering. Peeling the onion: the outer layers of Cryptococcus neoformans. Mem Inst Oswaldo Cruz. 113:e180040; doi: 10.1590/0074-02760180040, 2018. PMID: 29742198 PMCID: PMC5951675.

REVIEW ARTICLE: Zhuo A. Wang, Lucy X. Li, and Tamara L. Doering. Unraveling synthesis of the cryptococcal cell wall and capsule. Glycobiology; doi: 10.1093/glycob/cwy030. 2018. PMID: 29648596 PMCID: PMC6142866.

Christine C. Yokoyama, Megan T. Baldridge, Daisy W. Leung, Guoyan Zhao, Chandni Desai, Ta-Chiang Liu, Vladimir E. Diaz-Ochoa, Jeremy P. Huynh, Jacqueline M. Kimmey, Erica L. Sennott, Camaron R. Hole, Broc T. McCune, Sunmin Park, Kelly M. Storek, Caihong Wang, Seungmin Hwang, Ashley Viehmann Milam, Eric Chen, Tobias Kerrinnes, Michael N. Starnbach, Scott A. Handley, Indira U. Mysorekar, Paul M. Allen, Denise M. Monack, Tamara L. Doering, Renee M. Tsolis, Jonathan E. Dworkin, Christina L. Stallings, Gaya K. Amarasinghe, Craig A. Micchell, Herbert W. Virgin. LysMD3 is a type II membrane protein without anin vivo role in the response to a range of pathogens. Journal of Biological Chemistry, 293(16):6022-6038; doi: 10.1074/jbc.RA117.001246. 2018. PMID: 29496999 PMCID: PMC5912457.

Ezekiel J. Maier, Brian C. Haynes, Stacey R. Gish, Zhuo A. Wang, Michael L. Skowyra, Alyssa L. Marulli, Tamara L. Doering, and Michael R. Brent. Model-driven mapping of transcriptional networks reveals the circuitry and dynamics of virulence regulation. Genome Research, 25, 690-700; doi: 10.1101/gr.184101.114 2015. PMID: 25644834 PMCID: PMC4417117.

Felipe H. Santiago-Tirado, Tao Peng, Meng Yang, Howard C. Hang, and Tamara L. Doering. A Single Protein S-acyl Transferase Acts through Diverse Substrates to Determine Cryptococcal Morphology, Stress Tolerance, and Pathogenic Outcome. PLoS Pathogens, 11(5):e1004908; doi: 10.1371/journal.ppat.1004908, 2015. PMID: 25970403 PMCID: PMC4430228.

Stacey R. Gish, Ezekiel J. Maier, Brian C. Haynes, Felipe H. Santiago, Deepa L. Srikanta, Matt Williams, Erika C. Crouch, Shabaana Khader, Michael R. Brent, and Tamara L. Doering. Computational Analysis Reveals a Key Regulator of Cryptococcal Virulence and Determinant of Host Response. mBio, 7, 313-316. doi: 10.1128/mBio.00313-16, 2016. PMID: 27094327 PMCID: PMC4850258.

REVIEW ARTICLE: Felipe H. Santiago-Tirado and Tamara L. Doering. All about that fat: Lipid modification of proteins in Cryptococcus neoformans. Journal of Microbiology 54, 212-222. doi: 10.1007/s12275-016-5626-6, 2016. PMID: 26920881 PMCID: PMC4851765.

Christian Heiss, Michael L. Skowyra, Hong Liu, J. Stacey Klutts, Zhirui Wang, Matthew Williams, Deepa Srikanta, Stephen M. Beverley, Parastoo Azadi, and Tamara L. Doering. Unusual galactofuranose modification of a capsule polysaccharide in the pathogenic yeast Cryptococcus neoformans. J. Biol. Chem., 288, 10994-11003. doi: 10.1074/jbc.M112.441998, 2013. PMID: 23408430 PMCID: PMC3630864.

Therese Wohlschlager, Reto Buser, Michael L. Skowyra, Brian C. Haynes, Bernard Henrissat, Tamara L. Doering, Markus Künzler, and Markus Aebi. Identification of the galactosyltransferase of Cryptococcus neoformans involved in the biosynthesis of basidiomycete-type glycosylinositolphosphoceramide. Glycobiology, 11, 1210-1219; doi: 0.1093/glycob/cwt057, 2013. PMID: 23926231 PMCID: PMC3796374.

REVIEW ARTICLE: Deepa Srikanta, Felipe H. Santiago-Tirado, and Tamara L. Doering. Cryptococcus neoformans: Historical curiosity to modern pathogen. Yeast, 31, 47-60; doi: 10.1002/yea.2997, 2014. PMID: 24375706 PMCID: PMC3938112.

Pardeep Kumar, Christian Heiss, Felipe H. Santiago-Tirado, Ian Black, Parastoo Azadi, and Tamara L. Doering. Pbx proteins in Cryptococcus neoformans cell wall remodeling and capsule assembly. Eukaryotic Cell, 13, 560-71; doi: 10.1128/EC.00290-13, 2014. PMID: 24585882 PMCID: PMC4060484.

Zhuo A. Wang, Cara L. Griffith, Michael L. Skowyra, Nicole Salinas, Matthew Williams, Ezekiel J. Maier, Stacey R. Gish, Hong Liu, Michael R. Brent, and Tamara L. Doering. Cryptococcus neoformans dual GDP-mannose transporters and their role in biology and virulence. Eukaryotic Cell, 13, 832-42; doi: 10.1128/EC.00054-14, 2014. PMID: 24747214 PMCID: PMC4054277.

Sanjoy Paul, Tamara L. Doering, and W. Scott Moye-Rowley. Cryptococcus neoformans Yap1 is required for normal fluconazole and oxidative stress resistance. Fungal Genetics and Biology, 74C:1-9; doi: 10.1016/j.fgb.2014.10.015, 2014. PMID: 25445311 PMCID: PMC4293237.

REVIEW ARTICLE: Deepa Srikanta, Felipe H. Santiago-Tirado, and Tamara L. Doering. Cryptococcus neoformans: Historical curiosity to modern pathogen. Yeast, 31, 47-60; doi: 10.1002/yea.2997, 2014.PMID: 24375706 PMCID: PMC3938112.

REVIEW ARTICLE: Kyung J. Kwon-Chung, James A. Fraser, Tamara L. Doering, Zhuo A. Wang, Guilhem Janbon, Alexander Idnurm, and Yong-Sun Bahn. Cryptococcus neoformans and Cryptococcus gattii, the etiologic agents of cryptococcosis. Cold Spring Harbor Perspectives in Medicine, 2014. 4:a019760. doi: 10.1101/cshperspect.a019760. PMID: 24985132 PMCID: PMC4066639.

Brian C. Haynes, Michael L. Skowyra, Sarah J. Spencer, Stacey R. Gish, Matthew Williams, Elizabeth P. Held, Michael R. Brent, and Tamara L. Doering. Toward an integrated model of capsule regulation in Cryptococcus neoformans. PLoS Pathogens 7(12): e1002411. doi: 10.1371/journal.ppat.1002411, 2011. PMID: 22174677 PMCID: PMC3234223.

Pardeep Kumar, Meng Yang, Brian C. Haynes, Michael L. Skowyra, and Tamara L. Doering. Emerging themes in cryptococcal capsule synthesis. Current Opinion in Structural Biology 21:597-602; doi: 10.1016/j.sbi.2011.08.006, 2011. PMID: 21889889 PMCID: PMC3189294.

Deepa Srikanta, Meng Yang, Matthew Williams, and Tamara L. Doering. A sensitive high-throughput assay for evaulating host-pathogen interactions in Cryptococcus neoformans infection. PLoS ONE 6(7):e22773. doi: 10.1371/journal.pone.0022773, 2011. PMID: 21829509 PMCID: PMC3145667.

Morgann C. Reilly, Kazuhiro Aoki, Zhou A. Wang, Michael L. Skowyra, Matthew Williams, Michael Tiemeyer, and Tamara L. Doering. A xylosylphosphotransferase of Cryptococcus neoformansacts in protein O-glycan synthesis. J. Biol. Chem. 286:26888-99; doi: 10.1074/jbc.M111.262162, 2011. PMID: 21606487 PMCID: PMC3143648.

Indrani Bose and Tamara L. Doering. Efficient implementation of RNA interference in the pathogenic yeast Cryptococcus neoformans. Journal of Microbiological Methods, 86:156-9; doi: 10.1016/j.mimet.2011.04.014, 2011. PMID: 21554906 PMCID: PMC3163904.

REVIEW ARTICLE: Guilhem Janbon and Tamara L. Doering. Biosynthesis and genetics of the Cryptococcal capsule. In: Cryptococcus: From human pathogen to model yeast (Joseph Heitman, June Kwon-Chung, John Perfect, Arturo Casadevall, Thomas R. Kozel, eds.). ASM Press, Washington, DC, 2011. https://www.asmscience.org/content/book/10.1128/9781555816858.ch03?crawler=true.

Morgann C. Reilly, Steven B. Levery, Sherry A. Castle, J. Stcey Klutts, and Tamara L. Doering. A novel xylsoylphosphotransferase activity discovered in Cryptococcus neoformans. J. Biol. Chem. 284:3618-3627; doi: 10.1074/jbc.M109.056226, 2009. PMID: 19864415 PMCID: PMC2794727.

REVIEW ARTICLE: Tamara L. Doering. How sweet it is! Capsule formation and cell wall biogenesis in Cryptococcus neoformans. Annual Reviews of Microbiology, 63:223-247; doi: 10.1146/annurev.micro.62.081307.162753, 2009. PMID: 19575556 PMCID: PMC2880894.

Aki Yoneda and Tamara L. Doering. An unusual organelle in Cryptococcus neoformans links luminal pH and capsule biosynthesis. Fungal Genetics and Biology, 46:682-687; doi: 10.1016/j.fgb.2009.05.001, 2009. PMID: 19450701 PMCID: PMC2755570.

REVIEW ARTICLE: Morgann C. Reilly and Tamara L. Doering. Biosynthesis of fungal and yeast glycans. In:  Microbial Glycobiology: Structures, Relevance, and Applications (Anthony Moran, Patrick Brennan, Otto Holst, and Mark von Itzstein, eds.), Elsevier Press, Inc., San Diego, CA,2009. https://doi.org/10.1016/B978-0-12-374546-0.00022-5.

Christian Heiss, J. Stacey Klutts, Zhirui Wang, Tamara L. Doering, and Parastoo Azadi. The structure of Cryptococcus neoformans galactoxylomannan contains beta-D-glucuronic acid. Carbohydrate Research, 344:915-920; doi: 10.1016/j.carres.2009.03.003, 2009. PMID: 19345342 PMCID: PMC2695399.

REVIEW ARTICLE: Richard D. Cummings and Tamara L. Doering. Chapter 21: Fungi, In: Essentials of Glycobiology, 2nd edition. (Ajit Varki, et al, editors). Cold Spring Harbor Press, Cold Spring Harbor, NY, 2008. [Text link]

Sherry A. Castle, Elizabeth Owuor, Stephanie H. Thompson, Michelle R. Garnsey, J. Stacey Klutts, Tamara L. Doering, and Steven B. Levery. Beta-1,2-xylosyltransferase Cxt1p is solely responsible for xylose incorporation into Cryptococcus neoformans glycosphingolipids. Eukaryotic Cell, 7, 1611-5; doi: 10.1128/EC.00458-07, 2008. PMID: 18676952 PMCID: PMC2547070.

J. Stacey Klutts and Tamara L. Doering. Cryptococcal xylosyltransferase 1 (Cxt1p) from Cryptocococus neoformans plays a direct role in the synthesis of capsule polysaccharides. J. Biol. Chem. 283, 14327-14334; doi: 10.1074/jbc.M708927200, 2008. PMID: 18347023 PMCID: PMC2386922.

Aki Yoneda and Tamara L. Doering. Regulation of Cryptococcus neoformans capsule size is mediated at the polymer level. Eukaryotic Cell, 7, 546-549; doi: 10.1128/EC.00437-07, 2008. PMID: 18156288 PMCID: PMC2268517.

J. Stacey Klutts, Steven B. Levery, and Tamara L. Doering. A beta-1,2-xylosyltransferase from Cryptococcus neoformans defines a new family of glycosyltransferases. J. Biol. Chem. 282, 17890-17899; doi: 10.1074/jbc.M701941200, 2007. PMID: 17430900

Tricia R. Cottrell, Cara L. Griffith, Hong Liu, Ashley A. Nenninger, and Tamara L. Doering. The pathogenic fungus Cryptococcus neoformans expresses two functional GDP-mannose transporters with distinct expression patterns and roles in capsule synthesis. Eukaryotic Cell, 6, 776-785; doi: 10.1128/EC.00015-07, 2007. PMID: 17351078 PMCID: PMC1899245.

Amy J. Reese, Aki Yoneda, Julia A. Breger, Anne Beauvais, Hong Liu, Cara L. Griffith, Indrani Bose, Myoung-Ju Kim, Colleen Skau, Sarah Yang, Julianne Sefko, Masako Osumi, Jean-Paul Latge, Eleftherios Mylonakis, and Tamara L. Doering. Loss of cell wall alpha(1-3) glucan affects Cryptococcus neoformans from ultrastructure to virulence. Molecular Microbiology, 63, 1385-1398; doi: 10.1111/j.1365-2958.2006.05551.x, 2007. PMID: 17244196 PMCID: PMC1864955.

Aki Yoneda and Tamara L. Doering. A eukaryotic capsular polysaccharide is synthesized intracellularly and secreted via exocytosis. Molecular Biology of the Cell, 17, 5131-5140; doi: 10.1091/mbc.e06-08-0701, 2006. PMID: 17021252 PMCID: PMC1679678.

REVIEW ARTICLE: J. Stacey Klutts, Aki Yoneda, Morgann Reilly, Indrani Bose, and Tamara L. Doering. Glycosyltransferases and their products: Cryptococcal variations on fungal themes. FEMS Yeast Research, 6, 499-512; doi: 10.1111/j.1567-1364.2006.00054.x, 2006. PMID: 16696646.

Stephen M. Beverley, Katherine L. Owens, Melissa Showalter, Cara L. Griffith, Tamara L. Doering, Victoria C. Jones, and Michael R. McNeil. Idenitfication of eukaryotic UDP-galactopyranose mutase in microbial and metazoal pathogens. Eukaryotic Cell, 4, 1147-1154; doi: 10.1128/EC.4.6.1147-1154.2005, 2005. PMID: 15947206 PMCID: PMC1151986.

Brendan Loftus et al. The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science, 307, 1321-1324; doi:  10.1126/science.1103773, 2005. PMID: 15653466 PMCID: PMC3520129.

Cara Griffith, J. Stacey Klutts, Lijuan Zhang, Steven B. Leverey, and Tamara L. Doering. UDP-glucose dehydrogenase plays multiple roles in the biology of the pathogenic fungus Cryptococcus neoformans. J. Biol. Chem. 279, 51669-51676; doi: 10.1074/jbc.M408889200, 2004. PMID: 15383535.

Aaron Tenney, Randall Brown, Charles Vasquez, Jennifer K. Lodge, Tamara L. Doering, and Michael R. Brent. Gene prediction and verification in a compact genome with numerous small introns. Genome Research, 14, 2330-2335; doi: 10.1101/gr.2816704, 2004. PMID: 15479946 PMCID: PMC525692.

Isabelle Mouyna, Christine Henry, Tamara L. Doering, and Jean-Paul Latge. Gene silencing with RNA interference in the human pathogenic fungus Aspergillus fumigatus. FEMS Microbiol. 237, 317-324; doi: 10.1016/j.femsle.2004.06.048, 2004. PMID: 15321679.

Jeramia J. Ory, Cara L. Griffith, and Tamara L. Doering. An efficiently regulated promoter system for Cryptococcus neoformans utilizing the CTR4 promoter. Yeast, 21, 919-926; doi: 10.1002/yea.1139, 2004. PMID: 15334556

Maor Bar-Peled, Cara L. Griffith, Jeramia J. Ory, and Tamara L. Doering. Biosynthesis of UDP-GlcA, a key metabolite for capsular polysaccharide synthesis in the pathogenic fungus Cryptococcus neoformans. Biochemical J., 381, 131-136; doi: 10.1042/BJ20031075, 2004.  PMID: 15030319 PMCID: PMC1133770.

Amy J. Reese and Tamara L. Doering. Cell wall alpha-1,3-glucan is required to anchor the Cryptococcus neoformans capsule. Molecular Microbiology, 50, 1401-1409; doi: 10.1046/j.1365-2958.2003.03780.x, 2003. PMID: 14622425.

Ulf Sommer, Hong Liu, and Tamara L. Doering. An alpha-1,3-mannosyltransferase of Cryptococcus neoformans. J. Biol. Chem., 278, 47724-47730; doi: 10.1074/jbc.M307223200, 2003. PMID: 14504286.

REVIEW ARTICLE: Tricia R. Cottrell and Tamara L. Doering. Silence of the strands: RNA interference in eukaryotic pathogens. Trends in Microbiology, 11, 37-43; doi: 10.1016/s0966-842x(02)00004-5, 2003. PMID: 12526853.

REVIEW ARTICLE: Indrani Bose, Amy J. Reese, Jeramia J. Ory, Guilhem Janbon, and Tamara L. Doering. A yeast under cover: The capsule of Cryptococcus neoformans. Eukaryotic Cell, 2, 655-663; doi: 10.1128/ec.2.4.655-663.2003, 2003. PMID: 12912884 PMCID: PMC178345.

Maor Bar-Peled, Cara L. Griffith, and Tamara L. Doering. Functional cloning and characterization of a UDP-glucuronic acid decarboxylase: The pathogenic fungus Cryptococcus neoformans elucidates UDP-xylose synthesis. Proc. Natl. Acad. Sci. USA, 98, 12003-12008; doi: 10.1073/pnas.211229198, 2001. PMID: 11593010 PMCID: PMC59757.

Hong Liu, Tricia R. Cottrell, Lynda M. Pierini, William E. Goldman, and Tamara L. Doering. RNA interference in the pathogenic fungus Cryptococcus neoformans. Genetics, 160, 463-470; doi: https://www.genetics.org/content/160/2/463.long, 2002. PMID: 11861553 PMCID: PMC1461992.

Lynda Pierini and Tamara L. Doering. Spatial and temporal sequence of capsule construction in Cryptococcus neoformans. Molecular Microbiology, 141, 105-115; doi: 10.1046/j.1365-2958.2001.02504.x, 2001. PMID: 11454204.

REVIEW ARTICLE: Tamara L. Doering. How does Cryptococcus get its coat? Trends in Microbiology, 8, 545-551; doi: 10.1016/s0966-842x(00)01890-4, 2000. PMID: 11115750.  [Response to a comment on this article Trends in Microbiology 9, p. 113 (2001).]

Tamara L. Doering. A unique alpha-1,3 mannosyltransferase of the pathogenic fungus Cryptococcus neoformans. J. Bacteriol., 181, 5482-5488; doi: http://10.1128/JB.181.17.5482-5488.1999, 1999. PMID: 10464224 PMCID: PMC94059.

Sarah P. Franzot and Tamara L. Doering. Inositol acylation of glycosylphosphatidylinositols in the pathogenic fungus Cryptococcus neoformans and the model yeast Saccharomyces cerevisiae. Biochem. J., 340, 25-32; doi: https://doi.org/10.1042/bj3400025, 1999. PMID: 10229655 PMCID: PMC1220218.

Lin-Chi Chen, David L. Goldman, Tamara L. Doering, Liise-anne Pirofski, and Arturo Casadevall. Antibody response to Cryptococcus neoformans proteins in rodents and humans. Infection & Immunity, 67, 2218-2224; doi: http://10.1128/IAI.67.5.2218-2224.1999, 1999. PMID: 10225877 PMCID: PMC115960.

Tamara L. Doering, Joshua D. Nosanchuk, Wendy K. Roberts and Arturo Casadevall. Melanin as a potential cryptococcal defence against microbicidal proteins. Medical Mycology, 37, 175-181; doi: http://10.1046/j.1365-280X.1999.00218.x, 1999. PMID: 10421849.


Non-crypto publications by Tamara L. Doering

Primary data papers

David A. Bernlohr, Tamara L. Doering, Thomas J. Kelly, Jr. and M. Daniel Lane. Tissue specific expression of p422 protein, a putative lipid carrier in mouse adipocytes. Biochem. Biophys. Res. Comm. 132, 850-855; doi: 10.1016/0006-291x(85)91209-4, 1985. PMID: 2415129.

David W. Saffen, Kathleen A. Presper, Tamara L. Doering and Saul Roseman. Sugar transport by the bacterial phosphotransferase system. Molecular cloning and structural analysis of the E. coli ptsH, ptsI, and crr genes. J. Biol. Chem. 262, 16241-16253; doi: https://www.jbc.org/content/262/33/16241.long,1987. PMID: 2960675.

James D. Bangs, Tamara L. Doering, Paul T. Englund and Gerald W. Hart. Biosynthesis of a variant surface glycoprotein of Trypanosoma brucei. Processing of the glycolipid membrane anchor and N-linked oligosaccharides. J. Biol. Chem. 263, 17697-17705; doi: https://www.jbc.org/content/263/33/17697.long, 1988. PMID: 3182868.

Wayne J. Masterson, Tamara L. Doering, Gerald W. Hart and Paul T. Englund. A novel pathway for glycan assembly: Biosynthesis of the glycosyl-phosphatidylinositol membrane anchor of the trypanosome variant surface glycoprotein. Cell 56, 793-800; doi: 10.1016/0092-8674(89)90684-3, 1989. PMID: 2924349.

Tamara L. Doering, Wayne J. Masterson, Paul T. Englund, and Gerald W. Hart. Biosynthesis of the glycosyl phosphatidylinositol membrane anchor of the trypanosome variant surface glycoprotein: Origin of the non-acetylated glucosamine. J. Biol. Chem. 264, 11168-11173; doi: https://www.jbc.org/content/264/19/11168.long, 1989. PMID: 2525555.

Jessica L. Krakow, Tamara L. Doering, Wayne J. Masterson, Gerald W. Hart and Paul T. Englund. A glycolipid from Trypanosoma brucei related to the variant surface glycoprotein membrane anchor. Mol. Biochem. Parasitol. 36, 263-270; doi: 10.1016/0166-6851(89)90174-6, 1989. PMID: 2797062.

Mark F. Bean, James D. Bangs, Tamara L. Doering, Paul T. Englund, Gerald W. Hart, Catherine Fenselau, and Robert J. Cotter. Assessing heterogeneity of the high-mannose glycopeptide gp432 on the variant surface glycoprotein of trypanosomes: A comparison of plasma desorption mass spectrometry and radiolabeling techniques. Anal. Chem., 61, 2686-2688; doi: 10.1021/ac00198a019, 1989. PMID: 2619054.

Wayne J. Masterson, Jayne Raper, Tamara L. Doering, Gerald W. Hart, and Paul T. Englund. Fatty acid remodeling: A novel reaction sequence in the biosynthesis of trypanosome glycosyl phosphatidylinositol membrane anchors. Cell, 62, 73-80; doi: 10.1016/0092-8674(90)90241-6, 1990. PMID: 1694728.

Tamara L. Doering, Jayne Raper, Laurence U. Buxbaum, Jeffrey I. Gordon, Steven P. Adams, Gerald W. Hart, and Paul T. Englund. An analog of myristic acid with selective toxicity for African trypanosomes. Science, 252, 1851-1854; doi: 10.1126/science.1829548, 1991. PMID: 1829548.

Tamara L. Doering, Melissa S. Pessin, Eleanor F. Hoff, Gerald W. Hart, Dan M. Raben, and Paul T. Englund. Trypanosome metabolism of myristate, the fatty acid required for the variant surface glycoprotein membrane anchor. J. Biol. Chem. 268, 9215-9222; doi: https://www.jbc.org/content/268/13/9215.long, 1993. PMID: 8486622.

Tamara L. Doering, Melissa S. Pessin, Gerald W. Hart, Daniel M. Raben, and Paul T. Englund. The fatty acids in unremodelled trypanosome glycosyl-phosphatidylinositols. Biochem. J., 299, 741-746; doi: 10.1042/bj2990741, 1994. PMID: 8192662 PMCID: PMC1138083.

Tamara L. Doering, Tianbao Lu, Karl A. Werbovetz, George Gokel, Gerald W. Hart, Jeffrey I. Gordon, and Paul T. Englund. Toxicity of myristic acid analogs towards African trypanosomes. Proc. Natl. Acad. Sci. USA, 91, 9735-9739; doi: 10.1073/pnas.91.21.9735, 1994. PMID: 7937882 PMCID: PMC44891.

Tamara L. Doering and Randy Schekman. GPI-anchor attachment is required for Gas1p transport from the endoplasmic reticulum in COP II vesicles. EMBO J., 15, 182-191; doi:https://doi.org/10.1002/j.1460-2075.1996.tb00346.x, 1996. PMID: 8598201 PMCID: PMC449930.

Christine Sütterlin, Tamara L. Doering, Frauke Schimmöller, Stephan Schröder and Howard Riezman. Specific requirements for the ER to Golgi transport of GPI-anchored proteins in yeast. J. Cell Science, 111, 2703-2714; doi: https://jcs.biologists.org/content/110/21/2703.long, 1997. PMID: 9427388.

Tamara L. Doering and Randy Schekman. Glycosyl-phosphatidylinositol anchor attachment in a yeast in vitro system. Biochem. J., 328, 669-675; doi: 10.1042/bj3280669, 1997. PMID: 9371730 PMCID: PMC1218970.

Reviews and Methods

Paul T. Englund, Jessica L. Krakow, Dale Hereld, Tamara L. Doering, Wayne J. Masterson and Gerald W. Hart. Biosynthesis of the trypanosome variant surface glycoprotein: Attachment of the glycolipid membrane anchor. In: Molecular Basis of the Action of Drugs and Toxic Substances (N. Castognoli, T.P. Singer and C.C. Wang, eds.) Walter de Gruyter, New York, 1987.

Dale Hereld, Jessica L. Krakow, Tamara L. Doering, Wayne J. Masterson, Gerald W. Hart, and Paul T. Englund. The membrane-anchoring glycolipid of the trypanosome variant surface glycoprotein. In: Post-Translational Modification of Proteins by Lipids (U. Brodbeck and C. Bordier, eds.) Springer-Verlag, Berlin, 1987.

Paul T. Englund, Dale Hereld, Jessica L. Krakow, Tamara L. Doering, Wayne J. Masterson and Gerald W. Hart. The glycolipid anchor of the trypanosome variant surface glycoprotein: Its biosynthesis and cleavage. In: The Biology of Parasitism (P. Englund and A. Sher, eds.), Alan R. Liss, Inc., New York, 1988.

Tamara L. Doering, Wayne J. Masterson, Gerald W. Hart, and Paul T. Englund. Biosynthesis of glycosyl phosphatidylinositol membrane anchors. J. Biol. Chem., 265, 611-614, 1990.

Tamara L. Doering, Jayne Raper, Laurence U. Buxbaum, Gerald W. Hart, and Paul T. Englund. Biosynthesis of glycosyl phosphatidylinositol protein anchors. Methods: A Companion to Methods in Enzymology, 1, 288-296, 1990.

Kojo Mensa-Wilmot, Tamara L. b, Jayne Raper, Laurence U. Buxbaum, Gerald W. Hart, and Paul T. Englund. Glycosyl phosphatidylinositol membrane anchors in African trypanosomes. In: Molecular and Immunological Aspects of Parasitism (C.C. Wang, ed.), AAAS Press, Washington, D. C., 1991.

Tamara L. Doering. Glycosyl phosphatidylinositol protein anchors of African trypanosomes: Biosynthesis and therapeutic implications. Ph.D. dissertation, Johns Hopkins University, 1991.

Jayne Raper, Tamara L. Doering, Lawrence U. Buxbaum, and Paul T. Englund. Glycosyl phosphatidylinositols in Trypanosoma brucei. Experimental Parasitology 76, 216-220, 1993.

Tamara L. Doering, Paul T. Englund, and Gerald W. Hart. Detection of glycophospholipid protein anchors on proteins. In: Current Protocols in Molecular Biology, F. A. Ausubel et al, Eds., Unit 17, Analysis of Glycoconjugates, Guest Eds. A. Varki and J. Coligan, Greene Publishing and Wiley-Interscience, NY. 1993.

Tamara L. Doering. Glycosylphosphoinositol linkages of membrane glycoproteins. In: Cell Surface and Extracellular Glycoconjugates: Structure and Function (David D. Roberts and Robert P. Mecham, eds.), Academic Press, Inc., Orlando, Fla. 1993.

Randy Schekman, Charles Barlowe, Sebastian Bednarak, Joe Campbell, Tamara Doering, Rainer Duden, Meta Kuehn, Michael Rexach, Tom Yeung, and Lelio Orci. Coat Proteins and selective protein packaging into transport vesicles. Cold Spring Harbor Symposium on Quantitative Biology, 60, 11-21, 1995.

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